Table 2.
28-Day Mortality according to Severity before and after IMV
| Mild | Moderate | Severe | P Value | |
|---|---|---|---|---|
| 28-d mortality in the HFNO group | ||||
| Severity based on blood gas within first 12 h on HFNO | 7.7% (1/13) | 19.3% (27/140) | 22.6% (7/31) | 0.327 |
| Severity based on last HFNO blood gas before IMV | 0.0% (0/3) | 32.7% (16/49) | 26.7% (16/60) | 0.768 |
| Severity based on first blood gas on IMV | 25.0% (5/20) | 29.0% (20/69) | 46.7% (7/15) | 0.202 |
| 28-d mortality in the NIV group | ||||
| Severity based on blood gas within first 12 h on NIV | 10.5% (2/19) | 21.2% (21/92) | 45.0% (9/20) | 0.012 |
| Severity based on last NIV blood gas before IMV | 25.0% (1/4) | 48.8% (21/43) | 40.9% (9/22) | 0.887 |
| Severity based on first blood gas on IMV | 46.2% (6/13) | 48.6% (17/35) | 38.9% (7/18) | 0.634 |
Definition of abbreviations: HFNO = high-flow nasal oxygen; IMV = invasive mechanical ventilation; NIV = noninvasive ventilation.