Table 3.
28-Day Mortality according to Different PaO2/FiO2 Cutoffs
| Blood gas within First 12 h of HFNO or NIV | Exclusively Treated with HFNO | Transitioned from HFNO to IMV | P for Fisher’s Exact Test | Exclusively Treated with NIV | Transitioned from NIV to IMV | P for Fisher’s Exact Test |
|---|---|---|---|---|---|---|
| PaO2/FiO2 ⩽300 mm Hg | 3/72 (4.2%) | 32/112 (28.6%) | <0.0001 | 1/62 (1.6%) | 31/69 (44.9%) | <0.0001 |
| PaO2/FiO2 ⩽250 mm Hg | 3/71 (4.2%) | 31/111 (27.9%) | <0.0001 | 1/59 (1.7%) | 31/65 (47.7%) | <0.0001 |
| PaO2/FiO2 ⩽200 mm Hg | 3/64 (4.7%) | 31/107 (29.0%) | <0.0001 | 1/53 (1.9%) | 29/59 (49.2%) | <0.0001 |
| PaO2/FiO2 ⩽150 mm Hg | 2/41 (4.9%) | 26/84 (31.0%) | 0.001 | 1/31 (3.2%) | 20/40 (50.0%) | <0.0001 |
| PaO2/FiO2 ⩽100 mm Hg | 0/4 (0.0%) | 7/27 (25.9%) | 0.55 | 0/4 (0.0%) | 9/16 (56.3%) | 0.0941 |
For definition of abbreviations, see Table 2.