Table 1.
Baseline Cohort Characteristics
| Sensitized and Exposed to Any Allergen | No Sensitization/Exposure Combinations | P Value | |
|---|---|---|---|
| n | 31 | 152 | |
| Age, yr | 65.8 (9.4) | 67.6 (7.9) | 0.3 |
| Female, n (%) | 16 (51.6) | 64 (42.1) | 0.3 |
| African American, n (%) | 12 (38.7) | 27 (17.8) | 0.009 |
| More than high school degree, n (%) | 25 (80.6) | 131 (86.2) | 0.4 |
| Pack-years smoked | 56.7 (39.1) | 54.3 (30.4) | 0.7 |
| Eosinophil count, cells/μl | 215.9 (127.7) | 210.4 (160.5) | 0.9 |
| Total IgE, kU/L | 492.9 (699.5) | 91.3 (248.6) | <0.001 |
| Season of dust assessment, n (%) | |||
| Winter | 10 (32.3) | 36 (23.7) | 0.3 |
| Spring | 4 (12.9) | 38 (25.0) | 0.1 |
| Summer | 10 (32.3) | 30 (19.7) | 0.1 |
| Fall | 7 (22.6) | 48 (31.6) | 0.3 |
| FEV1% predicted | 46.9 (18.5) | 54.4 (17.2) | 0.03 |
| SGRQ* | 49.5 (20.23) | 42.9 (17.5) | 0.06 |
| mMRC | 2.2 (1.2) | 2.1 (1.1) | 0.5 |
| Moderate or severe exacerbations in the last 3 mo, n (%) | 7 (24.1) | 27 (17.8) | 0.4 |
Definition of abbreviations: mMRC = modified Medical Research Council dyspnea score; SGRQ = St. George’s Respiratory Questionnaire.
Data are shown as mean (SD) unless otherwise indicated. Bold values are statistically significant.
*
Higher scores indicate higher morbidity.