Table 1.
Characteristics of the Discovery and Validation Populations
| Discovery GACRS (n = 1,151) | Validation CAMP (n = 911) | |
|---|---|---|
| Age, yr, mean (SD) | 9.22 (1.88) | 12.94 (2.14) |
| Sex, male, n (%) | 682 (59.3%) | 549 (60.3%) |
| Sex, female, n (%) | 469 (40.7%) | 362 (39.7%) |
| Height, cm, mean (SD) | 132.66 (11.85) | 155.89 (13.35) |
| Weight, kg, mean (SD) | 33.02 (11.49) | 53.23 (17.32) |
| BMI, kg/m2, mean (SD) | 18.28 (3.77) | 21.42 (4.70) |
| Race | ||
| White, n (%) | — | 630 (69.2%) |
| Black, n (%) | — | 117 (12.8%) |
| Hispanic, n (%)* | 1,151 (100%) | 84 (9.2%) |
| Other, n (%) | — | 80 (8.8%) |
| Treatment arm† | ||
| Budesonide, n (%) | — | 270 (29.6%) |
| Nedocromil, n (%) | — | 269 (29.5%) |
| Placebo, n (%) | — | 372 (40.8%) |
Definition of abbreviations: BMI = body mass index; CAMP = Childhood Asthma Management Program; GACRS = Genetics of Asthma in Costa Rica Study.
*
GACRS represents a unique population isolate where participants were selected on the basis of having six or more great-grandparents born within the central valley of Costa Rica.
†
The CAMP population was from a completed clinical trial.