Table 5.
Adverse events of the studies included EUS-biliary drainage versus percutaneous transhepatic cholangiography
| Study | Bories et al. | Bapaye et al. | Lu et al. | Artifon et al. | Bill et al. |
|---|---|---|---|---|---|
| Acute adverse events | |||||
| Bleeding | 3 versus5 | 0 versus 1 | 2 versus 5 | 1 versus 0 | 2 versus 1 |
| Subcapsular hematoma | – | – | – | – | – |
| Hemobilia | – | – | – | – | – |
| Perihepatic bile collection/biloma | – | – | – | 1 versus 0 | – |
| Recurrent abdominal pain | – | – | – | – | – |
| Cholangitis | 1 versus3 | 0 versus 2 | 2 versus 5 | – | – |
| Pancreatitis | – | – | – | – | 1 versus 0 |
| Pneumoperitoneum | – | – | – | – | – |
| Sepsis/infection of drain site | 5 versus 7 | 1 versus 2 | 0 versus 5 | – | – |
| Perihepatic abscess | – | – | – | – | – |
| Sheared guide wire | – | – | – | – | – |
| Hepatic abscess | – | – | – | 0 versus 2 | – |
| Peritonitis/bile leak | 1 versus1 | 4 versus0 | 0 versus 4 | 0 versus 1 | 1 versus 0 |
| Tube malposition | – | – | 0 versus2 | – | – |
| Venous fistula | – | – | – | – | – |
| External biliary fistula | 1 versus0 | 0 versus 7 | – | – | – |
| Chronic or delayed adverse events | |||||
| Recurrent biliary obstruction | – | – | – | – | 2 versus 5 |
| Deaths | 4 versus3 | 1 versus2 | – | – | – |
| Cholecystitis | – | – | – | – | 1 versus1 |
| Re-intervention/Repeat procedure | – | – | 2 versus17 | – | 4 versus15 |
| Overall cost of procedure (mean±SD) | NA | NA | NA | USD 5673 versus USD 7570 | NA |
|
| |||||
| Study | Khashab et al. | Lee et al. | Huang et al. | Giovannini et al. | Sharaiha et al. |
|
| |||||
| Acute adverse events | |||||
| Bleeding | 0 versus1 | – | 1 versus3 | 1 versus 4 | 2 versus1 |
| Subcapsular hematoma | 0 versus2 | – | 0 versus 2 | – | – |
| Hemobilia | 0 versus 5 | 0 versus1 | – | – | – |
| Perihepatic bile collection/biloma | 0 versus7 | – | – | – | 0 versus 1 |
| Recurrent abdominal pain | – | – | – | – | 0 versus 3 |
| Cholangitis | 0 versus3 | 0 versus5 | 1 versus0 | 1 versus 3 | – |
| Pancreatitis | 1 versus0 | 1 versus0 | – | – | 1 versus0 |
| Pneumoperitoneum | – | – | – | – | – |
| Sepsis/infection of drain site | 5 versus7 | 1 versus2 | 0 versus5 | – | – |
| Perihepatic abscess | 0 versus1 | – | – | – | 0 versus1 |
| Sheared guide wire | 1 versus0 | – | – | – | – |
| Hepatic abscess | – | – | – | 0 versus2 | – |
| Peritonitis/bile leak | 0 versus10 | 1 versus4 | 0 versus2 | 1 versus3 | 1 versus0 |
| Tube malposition | 0 versus2 | – | 0 versus2 | – | 0 versus4 |
| Venous fistula | 0 versus1 | – | – | – | – |
| External biliary fistula | – | – | – | – | – |
| Chronic or delayed adverse events | |||||
| Recurrent biliary obstruction | – | – | – | – | – |
| Deaths | – | – | – | 3 versus3 | – |
| Cholecystitis | 1 versus0 | – | – | – | – |
| Re-intervention/repeat procedure | 3 versus12 | 11 versus29 | – | – | 1 versus5 |
| Overall cost of procedure (mean±SD) | USD 9218±3772 versus USD 18.261±16.021 | NA | USD 15.35±5.51 versus USD 21.42±3.95 | NA | NA |
SD: Standard deviation; NA: Not applicable