Figure 4. E3 ligase ligands that are commonly used for PROTACs.
Derivatives of Thalidomide targeting Cereblon (CRBN) and the ligand of Von Hippel Lindau (VHL). The asterisk shows the point of attachment to the linker.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.