Table 3.
The Use of Immunological Adjuvants in Peptide-Based Nanovaccines Against Cervical Cancer
| Adjuvant Categories | Name and Composition | Mechanism |
|---|---|---|
| Aluminum salts | AS04: Alum, MPL | TLR4 |
| Emulsion-based adjuvant | MF59: Squalene, Tween 80, Span 85 | Oil-in-water formulation |
| IFA | Water-in-oil formulation | |
| Microbial derivative | CpG-ODN | TLR9 |
| Bacterial flagellin | TLR5 | |
| Lipid analogue | Lipopeptide: Pam2Cys | TLR1/2 |
| MPLA | TLR4 | |
| dsRNA analogue | Poly(I:C) | TLR3 |
| Cytokine | GM-CSF | Immunostimulatory complexes |