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. 2022 Feb 25;17:869–900. doi: 10.2147/IJN.S269986

Table 3.

The Use of Immunological Adjuvants in Peptide-Based Nanovaccines Against Cervical Cancer

Adjuvant Categories Name and Composition Mechanism
Aluminum salts AS04: Alum, MPL TLR4
Emulsion-based adjuvant MF59: Squalene, Tween 80, Span 85 Oil-in-water formulation
IFA Water-in-oil formulation
Microbial derivative CpG-ODN TLR9
Bacterial flagellin TLR5
Lipid analogue Lipopeptide: Pam2Cys TLR1/2
MPLA TLR4
dsRNA analogue Poly(I:C) TLR3
Cytokine GM-CSF Immunostimulatory complexes