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. 2022 Jan 30;14(1):e21740. doi: 10.7759/cureus.21740

Table 3. Components of Pfizer versus Moderna vaccine versus Janssen.

References [26-28]

Pfizer vaccine (BioNTech) Moderna vaccine (mRNA-1273) Janssen (JNJ-78436735)
Messenger ribonucleic acid (mRNA) Messenger ribonucleic acid (mRNA) Recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein
Lipids (their main role is to protect the mRNA and provide somewhat of a “greasy” exterior that helps the mRNA slide inside the cells). ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2 [(polyethylene glycol)-2000]-N, N-ditetradecylacetamide 1,2-distearoyl-snglycero-3- phosphocholine cholesterol. Lipids (require lipids to help deliver the mRNA to the cells.) SM-102 1,2-dimyristoyl-rac-glycero3-methoxypolyethylene glycol-2000 (PEG2000-DMG) cholesterol 1,2-distearoyl-snglycero-3-phosphocholine (DSPC).  
Salts (to help balance the acidity in our body): potassium chloride, monobasic potassium phosphate, sodium chloride, dibasic sodium phosphate dihydrate. Salt: sodium acetate Salt: trisodium citrate dihydrate
Sugar (helps the molecules maintain their shape during freezing). Basic table sugar, also known as sucrose, can also be found in the new COVID vaccine. This ingredient helps the molecules maintain their shape during freezing. Sugar: sucrose Sugars: 2-hydroxypropyl-β-cyclodextrin (HBCD) polysorbate-80, sodium chloride
  Acids: acetic acid, acid stabilizers, tromethamine and tromethamine hydrochloride Acids: citric acid monohydrate
- - Other ingredients: ethanol