Table 4.
Secondary outcomes by H2FPEF score group.
| Low score | Intermediate score* | High score⁎ | p-Value | |
|---|---|---|---|---|
| n | 40 | 72 | 44 | |
| During initial admission | ||||
| In-hospital mortality (%) | 3 (7.5) | 7 (9.7) | 8 (18.2) | 0.250 |
| ICU level of care (%) | 10 (25.0) | 24 (33.3) | 22 (50.0) | 0.048 |
| Mechanical ventilation (%) | 5 (12.5) | 11 (15.3) | 5 (11.4) | 0.818 |
| Length of stay (median (IQR)) | 4.00 [2.00, 10.00] | 6.00 [3.00, 10.00] | 7.50 [3.75, 15.25] | 0.118 |
| 60-day outcomes | ||||
| Readmission (%) | 7 (17.5) | 21 (29.2) | 17 (38.6) | 0.102 |
| Life-threatening arrhythmia (%) | 2 (5.0) | 5 (6.9) | 3 (6.8) | 0.914 |
| DVT (%) | 0 (0.0) | 2 (2.8) | 2 (4.5) | 0.415 |
| HF exacerbation† (%) | 0 (0.0) | 1 (1.4) | 5 (11.4) | 0.009 |
| Requiring RRT (%) | 2 (5.0) | 5 (6.9) | 4 (9.1) | 0.764 |
| PE (%) | 1 (2.5) | 2 (2.8) | 1 (2.3) | 0.986 |
| Total MACE (%) | 2 (5.0) | 5 (6.9) | 6 (13.6) | 0.304 |
| Myocardial injury‡ (%) | 1 (2.5) | 4 (5.6) | 4 (9.1) | 0.431 |
| Stroke (%) | 0 (0.0) | 0 (0.0) | 1 (2.3) | 0.278 |
| Cardiovascular death (%) | 1 (2.5) | 2 (2.8) | 2 (4.5) | 0.835 |
ICU = intensive care unit; IQR = interquartile range; MACE = Major adverse cardiac events; HF = heart failure; RRT = renal replacement therapy.
⁎
Low, intermediate, and high score groups defined as H2FPEF scores from 0 to 2, 3–5, and 6–9, respectively.
†
Defined as having the signs and symptoms consistent with a heart failure exacerbation.
‡
Myocardial injury defined as cardiac troponin greater than the upper limit of normal.