Figure 2.

FA inhibits DA neurodegeneration induced by 6-OHDA in BZ555 worms. (a) Representative images of DA neurons with GFP signals were captured in BZ555 worms treated with FA (50 μM) or L-Dopa (2 mM) in the presence or absence of 6-OHDA (50 mM) for 72 h. Scale bars: 20 μm. (b) The bar chart indicates the GFP intensity representing the content of DA neurons in BZ555 worms, which was quantified by using the ImageJ software. (c) The bar chart indicates the relative slowing rate (%) of BZ555 worms treated with FA (50 μM) or L-Dopa (2 mM) in the presence or absence of 6-OHDA (50 mM) for 72 h. Data were collected from at least 20 worms and expressed as the mean ± SD. ^∗∗p ≤ 0.01 and ^∗∗∗p ≤ 0.001.