Figure 5.

FA inhibits α-synuclein pathology in NL5901 worms via autophagy induction. (a) NL5901 worms fed with HT115 bacteria or RNAi bacteria of lgg-1, vps-34, or unc-51 genes were treated with or without FA (50 μM) for 7 days. Representative images with GFP signals were captured by using a fluorescence microscope. Scale bars: 100 μm. (b) The bar chart indicates the relative GFP intensity representing the expression of α-synuclein proteins in NL5901 worms. (c) The bar chart indicates the number of body bends of NL5901 worms in 20 s. Data were collected from at least 20 worms and were expressed as the mean ± SD. ^nsp > 0.05 and ^∗∗p ≤ 0.01.