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. 2022 Mar;28(3):608–616. doi: 10.3201/eid2803.211499

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Plasmodium falciparum parasite density and antigen levels by pfhrp2/3 genotype in study of Plasmodium falciparum malaria-infected participants, Ethopia, Kenya, Madagascar, and Rwanda, 2016–2018. A) Peripheral blood parasite density as determined by light microscopy. B) Log-transformed assay signal to pAldolase, pLDH, and HRP2/3 antigens. Boxes display interquartile range, horizontal lines within boxes indicate medians, and whiskers indicate 1.5× interquartile range. Significant differences in means are indicated with corresponding p values. Within each plot, all other differences among genotypes did not reach statistical significance at α = 0.05. HRP2/3, histidine-rich protein 2/3; ln (MFI-bg), log-transformed median fluorescence intensity minus background value; pAldolase, pan-Plasmodium aldolase; pLDH, pan-Plasmodium lactate dehydrogenase.