Table 4.

Cox proportional–hazards regression analysis of significant predictor in cerebral aneurysmal rerupture.

		N	Person months	Rerupture		Bivariable analysis (crude)			Multivariable analysis (adjusted)
				Event	Incidence	HR	95% C.I.	P-value	HR	95% C.I.	P-value
DM	No	140	4897	75	15.3	1.000
	Yes	31	1667	8	4.8	0.398	0.192–0.825	0.013
Smoking	No	150	5981	69	11.5	1.000			1.000
	Yes	21	583	14	24.0	1.713	0.963–3.047	0.067	2.109	1.170–3.799	0.013
Multiple aneurysms	1	157	6232	73	11.7	1.000			1.000
	2	14	332	10	30.2	1.709	0.881–3.314	0.113	2.775	1.378–5.592	0.004
Pre-OP Hunt and Hess scale	≤ 2	107	4435	44	9.9	1.000
	>2	64	2129	39	18.3	1.652	1.073–2.544	0.023
Pre-OP mRS	≤ 2	94	4284	32	7.5	1.000
	>2	77	2279	51	22.4	2.450	1.572–3.819	<0.001
Post-OP mRS (immediate)	≤ 2	72	3748	16	4.3	1.000			1.000
	>2	99	2816	67	23.8	4.303	2.488–7.442	<0.001	5.209	2.922–9.288	<0.001
Post-OP mRS (6 months later)	≤ 2	101	4572	35	7.7	1.000
	>2	70	1991	48	24.1	2.586	1.670–4.006	<0.001
ICA	No	88	2703	54	20.0	1.000
	Yes	83	3860	29	7.5	0.491	0.313–0.773	0.002
ACA	No	144	6021	63	10.5	1.000			1.000
	Yes	27	543	20	36.8	2.261	1.363–3.751	0.002	1.996	1.190–3.349	0.009
Pcom	No	163	6421	76	11.8	1.000			1.000
	Yes	8	143	7	49.0	2.372	1.092–5.151	0.029	2.934	1.313–6.556	0.009

HR, hazard ratio; Incidence, per 1,000 person-months.