Figure 5.
Volcano plots for associations between the individual pretransplant non-HLA antibodies and the occurrence of ABMRh in the absence of HLA-DSA (N=774). The plot depicts the p-values and the Hazard ratios of the univariable Cox regression analysis for antibodies against 78 different targets. For three non-HLA targets, IL-21, Actin and FN1, no estimations were obtained from the Cox analysis due to the low number of positive patients. In this analysis patients were censored at the time of the last performed biopsy or at de novo HLA-DSA occurrence.