TABLE 2.

Weekday circadian alignment (Thursday DLMO-midsleep) predicting neural response (standardized score) during pre-weekend reward anticipation (Friday fMRI).

Pre-weekend reward anticipation		Deviation model				Tertile modela
Striatal response	Core model	b	SE	t-value	p-value	b	SE	t-value	p-value
	Intercept	4.15	3.22	1.29	0.216	2.23	3.6	0.62	0.544
	Age	−0.16	0.14	−1.14	0.272	−0.1	0.16	−0.6	0.559
	Sex	−0.45	0.34	−1.33	0.201	−0.21	0.4	−0.52	0.613
	Racial identity	−0.11	0.26	−0.41	0.691	0.11	0.29	0.37	0.716
	Scan visit	0.64	0.36	1.81	0.089	0.51	0.39	1.32	0.206
	DLMO-midsleep - short	−1.12	0.33	−3.38	0.004c	−1.28	0.46	−2.82	0.012c
	DLMO-midsleep - long	0.04	0.19	0.20	0.848	−0.46	0.52	−0.89	0.389
	Core model + prior night’s TST b
	Thursday night TST	0.06	0.15	0.37	0.719	0.24	0.19	1.29	0.223
	DLMO-midsleep - short	−1.21	0.31	−3.94	0.002c	−1.60	0.49	−3.29	0.006c
	DLMO-midsleep - long	0.16	0.19	0.86	0.406	−0.93	0.59	−1.58	0.139
mPFC response	Core model
	Intercept	0.32	2.74	0.12	0.908	−0.99	2.87	−0.35	0.734
	Age	−0.06	0.12	−0.48	0.636	−0.01	0.13	−0.12	0.91
	Sex	0.07	0.29	0.25	0.808	0.27	0.32	0.84	0.416
	Racial identity	0.46	0.22	2.08	0.054	0.59	0.24	2.53	0.022
	Scan visit	0.70	0.30	2.32	0.034	0.58	0.31	1.88	0.078
	DLMO-midsleep - short	−1.08	0.28	−3.82	0.002c	−1.26	0.36	−3.46	0.003c
	DLMO-midsleep - long	0.24	0.16	1.49	0.156	−0.54	0.41	−1.32	0.206
	Core model + prior night’s TST b
	Thursday night TST	−0.22	0.13	−1.71	0.113	−0.12	0.16	−0.74	0.47
	DLMO-midsleep - short	−1.04	0.27	−3.87	0.002c	−1.28	0.42	−3.08	0.010c
	DLMO-midsleep - long	0.21	0.17	1.24	0.238	−0.50	0.50	−0.99	0.344

^a“Medium” DLMO-midsleep was the referent group for Tertile Models. Thus, coefficient estimates for phase angle “DLMO-midsleep - short” and “DLMO-midsleep - long” indicate changes relative to the “medium” phase angle group, respectively.

^bThe model adding prior night’s total sleep time (TST) includes all the covariates included in the Core model, but they are not listed for clarity of presentation. All covariate effects remained non-significant in subsequent models.

^cOutcome survived Benjamin-Hochberg multiple comparison correction. Bolded values indicate p < 0.05.