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. 2021 May 14;43(3):505–519. doi: 10.1038/s41401-021-00660-1

Fig. 4. MiRNA/lncRNA performs as upstream mediators to influence renal fibrosis in an epigenetic way.

Fig. 4

By improvement of advanced delivery technique, specific target therapy for fibrosis within the kidney tissue can be achieved. Popular loading systems (including viral vector, polymeric vector, liposome, exosome, etc.) are employed to deliver exact miRNA, lncRNA, according siRNA or ASO to the kidney.