Table 3.
Gut microbial characteristics and allergic rhinitis.
| Allergic rhinitis (n = 186) | Control (n = 106) | P-value | |
|---|---|---|---|
| Alpha-diversity | |||
| Number of OTUs observed | 295.3 ± 98.9 | 304.3 ± 100.0 | 0.412 |
| Chao 1 | 518.9 ± 206.0 | 548.4 ± 215.7 | 0.224 |
| ACE | 528.2 ± 217.2 | 557.1 ± 221.3 | 0.246 |
| Shannon’s index | 5.04 ± 0.64 | 5.07 ± 0.55 | 0.978 |
| Genus-level relative abundance, % | |||
| Bacteroides | 19.44 ± 11.28 | 18.17 ± 11.45 | 0.440 |
| Prevotella | 6.49 ± 13.99 | 11.72 ± 17.52 | 0.015 |
| Blautia | 11.20 ± 6.14 | 10.23 ± 6.65 | 0.070 |
| Bifidobacterium | 10.41 ± 10.53 | 7.97 ± 9.57 | 0.048 |
| Fusicatenibacter | 3.85 ± 3.56 | 4.15 ± 3.95 | 0.717 |
| Faecalibacterium | 3.49 ± 2.81 | 3.66 ± 3.25 | 0.951 |
| Collinsella | 4.47 ± 5.08 | 3.30 ± 3.27 | 0.072 |
| Parabacteroides | 2.35 ± 2.19 | 3.06 ± 3.79 | 0.156 |
| Megamonas | 2.38 ± 5.87 | 2.19 ± 5.65 | 0.859 |
| Streptococcus | 2.23 ± 4.67 | 2.08 ± 4.34 | 0.224 |
| Anaerostipes | 2.19 ± 2.52 | 1.75 ± 2.01 | 0.177 |
| Roseburia | 1.73 ± 2.44 | 1.61 ± 1.73 | 0.585 |
| Lachnoclostridium | 1.39 ± 1.40 | 1.58 ± 1.73 | 0.161 |
| Holdemanella | 1.31 ± 3.67 | 1.08 ± 2.35 | 0.103 |
| Dorea | 1.03 ± 0.82 | 0.95 ± 0.87 | 0.397 |
| Fusobacterium | 0.80 ± 2.69 | 0.94 ± 1.93 | 0.113 |
| Faecalicatena | 1.07 ± 1.33 | 0.89 ± 1.19 | 0.401 |
| Eubacterium | 0.61 ± 0.67 | 0.84 ± 1.22 | 0.505 |
| Catenibacterium | 0.57 ± 2.16 | 0.72 ± 2.13 | 0.310 |
| Sutterella | 0.62 ± 0.88 | 0.65 ± 0.74 | 0.168 |
| Phascolarctobacterium | 0.52 ± 0.66 | 0.65 ± 0.89 | 0.681 |
| Megasphaera | 0.46 ± 1.12 | 0.63 ± 1.51 | 0.729 |
| Prevotellamassilia | 0.20 ± 0.96 | 0.53 ± 2.22 | 0.250 |
| Coprococcus | 0.54 ± 1.09 | 0.51 ± 0.96 | 0.784 |
| Lactobacillus | 0.66 ± 1.50 | 0.48 ± 0.84 | 0.887 |
| Faecalimonas | 0.35 ± 0.83 | 0.43 ± 1.07 | 0.376 |
| Anaerobutyricum | 0.38 ± 0.42 | 0.42 ± 0.45 | 0.592 |
| Mitsuokella | 0.26 ± 1.09 | 0.40 ± 1.35 | 0.578 |
| Erysipelatoclostridium | 0.40 ± 0.75 | 0.37 ± 0.80 | 0.202 |
| Veillonella | 0.50 ± 1.48 | 0.37 ± 1.12 | 0.815 |
| Dialister | 0.30 ± 0.72 | 0.36 ± 0.83 | 0.802 |
| Butyricicoccus | 0.36 ± 0.27 | 0.36 ± 0.30 | 0.838 |
| Alistipes | 0.35 ± 0.44 | 0.32 ± 0.39 | 0.911 |
| Clostridium | 0.43 ± 2.72 | 0.30 ± 0.93 | 0.182 |
| Paraprevotella | 0.19 ± 0.44 | 0.28 ± 0.59 | 0.127 |
| Romboutsia | 0.33 ± 0.81 | 0.28 ± 0.45 | 0.905 |
| Escherichia | 0.62 ± 2.60 | 0.26 ± 1.21 | 0.001 |
| Robinsoniella | 0.38 ± 0.97 | 0.26 ± 0.56 | 0.590 |
| Lachnospira | 0.20 ± 0.46 | 0.24 ± 0.49 | 0.871 |
| Parasutterella | 0.27 ± 0.58 | 0.18 ± 0.41 | 0.133 |
Values are shown as the mean ± standard deviation. P-values were calculated using the Wilcoxon rank sum test. No adjustments were made for statistical tests shown in this table. OTU indicates operational taxonomic unit.