. Author manuscript; available in PMC: 2023 Mar 1.

Published in final edited form as: Mamm Genome. 2021 Sep 2;33(1):230–240. doi: 10.1007/s00335-021-09907-y

Table 5.

Tumor Models Characterized in SCID pigs

SCID Model	Cancer type	Location	Reference
ARTEMIS ^−/−	Melanoma	Orthotopic	(Basel et al. 2012)
ARTEMIS ^−/−	Pancreatic	Ectopic; subcutaneous	(Basel et al. 2012)
ARTEMIS ^−/−	Ovarian	Ectopic; subcutaneous	(Boettcher et al. 2019)
RAG2 ^−/−	Epithelial carcinoma	Orthotopic; metastases in SLN	(Kurihara et al. 2019)
IL2RG ^−/Y	HCC	Orthotopic	(Mishima et al. 2021)
RAG^−/− IL2RG^−/Y	Pancreatic	Ectopic; subcutaneous	(Hendricks-Wenger et al. 2021)

Note.— HCC = hepatocellular carcinoma, SLN = sentinel lymph node