TABLE 3.

Cohort effects in repeated measurement ANOVA analyses on locomotion assay endpoints. Bold font indicates significance at a p < 0.05 threshold.

Locomotion endpoint	Baseline	Dark	Light
Total movement counts	df = 2 F = 5.013 p = 0.007	df = 2 F = 0.870 p = 0.420	df = 2 F = 0.637 p = 0.529
Total movement duration	df = 2 F = 4.462 p = 0.012	df = 2 F = 0.120 p = 0.887	df = 2 F = 0.61 p = 0.941
Total movement distance	df = 2 F = 10.10 p = 0.001	df = 2 F = 6.358 p = 0.002	df = 2 F = 5.871 p = 0.003
Total movement speed	df = 2 F = 6.287 p = 0.002	df = 2 F = 22.63 p = 0.001	df = 2 F = 1.169 p = 0.312
Short movement counts	df = 2 F = 4.578 p = 0.011	df = 2 F = 1.013 p = 0.365	df = 2 F = 0.999 p = 0.370
Short movement duration	df = 2 F = 1.763 p = 0.174	df = 2 F = 10.63 p = 0.001	df = 2 F = 8.238 p = 0.001
Short movement distance	df = 2 F = 2.620 p = 0.075	df = 2 F = 12.105 p = 0.001	df = 2 F = 9.279 p = 0.001
Short movement speed	df = 2 F = 4.058 p = 0.018	df = 2 F = 2.596 p = 0.077	df = 2 F = 3.525 p = 0.031
Long movement counts	df = 2 F = 5.141 p = 0.006	df = 2 F = 1.100 p = 0.335	df = 2 F = 0.618 p = 0.540
Long movement duration	df = 2 F = 7.918 p = 0.001	df = 2 F = 7.074 p = 0.001	df = 2 F = 8.923 p = 0.001
Long movement distance	df = 2 F = 12.283 p = 0.001	df = 2 F = 14.594 p = 0.001	df = 2 F = 11.56 p = 0.001
Long movement speed	df = 2 F = 13.72 p = 0.001	df = 2 F = 13.79 p = 0.001	df = 2 F = 1.959 p = 0.143