TABLE 2.
Demographic, bacteriological, phenotypic resistance, and clinical characteristics of genomic clustered and non-clustered cases in Shanghai, China, 2009–2018.
| Characteristics | Clustered (N = 94) |
Non-clustered (N = 251) |
Total (N = 345) |
χ2 | P | |||
| N | % | N | % | N | % | |||
| Sex | 0.36 | 0.55 | ||||||
| Male | 79 | 84.04 | 204 | 81.27 | 283 | 82.03 | ||
| Female | 15 | 15.96 | 47 | 18.73 | 62 | 17.97 | ||
| Age* (y) | ||||||||
| 15–24 | 15 | 15.96 | 27 | 10.76 | 42 | 12.17 | Ref | – |
| 25–34 | 10 | 10.64 | 24 | 9.56 | 34 | 9.85 | 0.34 | 0.56 |
| 35–44 | 7 | 7.45 | 17 | 6.77 | 24 | 6.96 | 0.29 | 0.59 |
| 45–54 | 14 | 14.89 | 28 | 11.16 | 42 | 12.18 | 0.05 | 0.82 |
| 55–64 | 23 | 24.47 | 31 | 12.35 | 54 | 15.65 | 0.47 | 0.49 |
| 65≥ | 25 | 26.60 | 124 | 49.40 | 149 | 43.19 | 6.77 | 0.01 |
| Census register | 3.94 | 0.04 | ||||||
| Resident | 82 | 87.23 | 195 | 77.69 | 277 | 80.29 | ||
| Migrant | 12 | 12.77 | 56 | 22.31 | 68 | 19.71 | ||
| Occupation | 4.50 | 0.03 | ||||||
| Student | 11 | 11.70 | 13 | 5.18 | 24 | 6.96 | ||
| Non-student | 83 | 88.30 | 238 | 94.82 | 321 | 93.04 | ||
| TB-history | 1.88 | 0.17 | ||||||
| Yes | 17 | 18.09 | 31 | 12.35 | 48 | 13.91 | ||
| No | 77 | 81.91 | 220 | 87.65 | 297 | 86.09 | ||
| Beijing genotype strains | 5.76 | 0.02 | ||||||
| Yes | 88 | 93.62 | 210 | 83.67 | 298 | 86.38 | ||
| No | 6 | 6.38 | 41 | 16.33 | 47 | 13.62 | ||
| MDR-TB† | 0.26 | |||||||
| Yes | 7 | 7.45 | 10 | 3.98 | 17 | 4.93 | ||
| No | 87 | 92.55 | 241 | 96.02 | 328 | 95.07 | ||
| Resistance to INH | 7.11 | 0.01 | ||||||
| Yes | 19 | 20.21 | 24 | 9.56 | 43 | 12.46 | ||
| No | 75 | 79.79 | 227 | 90.44 | 302 | 87.54 | ||
| Drug resistance | 6.43 | 0.01 | ||||||
| Yes | 22 | 23.40 | 31 | 12.35 | 53 | 15.36 | ||
| No | 72 | 76.60 | 220 | 87.65 | 292 | 84.64 | ||
| Health system delay | 6.45 | 0.01 | ||||||
| <14 days | 71 | 75.53 | 218 | 86.85 | 289 | 83.77 | ||
| ≥14 days | 23 | 24.47 | 33 | 13.15 | 56 | 16.23 | ||
| Source of patients** | 1.95 | 0.38 | ||||||
| Clinical consultation | 35 | 37.23 | 98 | 39.8 | 133 | 39.00 | ||
| Referral | 58 | 61.70 | 140 | 56.68 | 198 | 58.06 | ||
| Others | 1 | 1.06 | 9 | 3.64 | 10 | 2.93 | ||
| Complications** | 0.42 | 0.51 | ||||||
| Yes | 7 | 7.45 | 24 | 9.72 | 31 | 9.09 | ||
| No | 87 | 92.55 | 223 | 90.28 | 310 | 90.91 | ||
| Sputum smear** | 0.56 | 0.45 | ||||||
| Yes | 63 | 67.74 | 174 | 71.9 | 237 | 70.75 | ||
| No | 30 | 32.26 | 68 | 28.1 | 98 | 29.25 | ||
| Cavity** | 0 | 0.99 | ||||||
| Yes | 33 | 35.11 | 85 | 35.12 | 118 | 35.12 | ||
| No | 61 | 64.89 | 157 | 64.88 | 218 | 64.88 | ||
*Univariate logistic analysis, Ref, reference.
†Represents the P-value calculated by Fisher’s exact probability method.
**The clinical information of some samples was missing.
The bold values mean these factors were statistically significant.