Table 1.
Baseline characteristics and ART outcomes of the participants included in the study.
| Clinical parameters, mean ± SD | Control | Advanced age | p-value a |
|---|---|---|---|
| (n = 15) | (n = 15) | ||
| Maternal age (years) | 29.93 ± 2.31 | 42.27 ± 2.43 | <0.001 |
| BMI (kg/m²) | 22.14 ± 4.04 | 23.05 ± 2.36 | 0.456 |
| Duration of infertility (years) | 3.20 ± 2.57 | 3.73 ± 2.79 | 0.590 |
| Number of previous cycles received (n) | 1.33 ± 0.49 | 1.87 ± 1.19 | 0.119 |
| Antral follicle count (n) | 14.71 ± 5.27 | 9.07 ± 2.94 | 0.001 |
| Basal FSH (IU/L) | 5.48 ± 1.41 | 8.01 ± 2.85 | 0.008 |
| Basal LH (IU/L) | 4.24 ± 3.14 | 3.81 ± 1.18 | 0.637 |
| Basal E2(pmol/L) | 125.67 ± 65.78 | 144.39 ± 85.54 | 0.532 |
| Basal Prl (mIU/L) | 19.89 ± 11.45 | 14.67 ± 6.71 | 0.200 |
| Basal P (nmol/L) | 1.92 ± 0.89 | 2.38 ± 1.29 | 0.300 |
| Basal T (nmol/L) | 0.84 ± 0.46 | 0.68 ± 0.43 | 0.409 |
| Total gonadotropin dose (IU) | 2130.83 ± 778.29 | 2775.00 ± 1027.51 | 0.067 |
| Duration of stimulation (days) | 10.33 ± 1.84 | 9.86 ± 2.60 | 0.571 |
| Endometrial thickness on day of hCG (cm) | 1.02 ± 0.21 | 1.07 ± 0.26 | 0.595 |
| Number of oocytes retrieved (n) | 14.60 ± 6.56 | 6.33 ± 4.72 | <0.001 |
| Number of 2PN embryos (n) | 7.33 ± 3.85 | 3.13 ± 2.53 | 0.001 |
| Number of cleaved embryos (n) | 6.80 ± 3.99 | 2.60 ± 2.16 | 0.001 |
ART, assisted reproductive technology; SD, standard deviation; BMI, body mass index; FSH, follicle stimulating hormone; LH, luteinizing hormone; E2, estradiol; Prl, prolactin; P, progesterone; T, testosterone; hCG, human chorionic gonadotropin; 2PN, two pronuclei.
aCharacteristics between the control group and advanced age group were compared with t-test. The p-values in bold text mean statistically significant (p < 0.05).