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. 2022 Feb 16;13:794528. doi: 10.3389/fphar.2022.794528

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Copyright © 2022 Duan, Li, Liu, Sun, Wu, Chen, Guo and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of YTC on PI3K/Akt signaling pathway in H₂O₂-induced H9c2 cells. (A) WB images of C-caspase-3, Bcl-2, Bax, p-Akt, p-PI3K, AKT and PI3K protein expression. (B) Analysis of C-caspase-3. (C) Analysis of Bcl-2. (D) Analysis of Bax. (E) Analysis of p-Akt. (F) Analysis of p-PI3K. (G) IF images of p-PI3K and PI3K. (H) Analysis of the p-PI3K/PI3K ratio. (I) IF images of p-Akt and Akt. (J) Analysis of the p-Akt/Akt ratio. (K) IF images of Bcl-2 and Bax. (L) Analysis of the Bcl-2/Bax ratio. Data were expressed as mean ± SD (n = 3), **p < 0.05 and **p < 0:01 vs model.