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editorial
. 2022 Feb 21;11:e13. doi: 10.1017/jns.2022.11

Table 2.

Potential yield of vitamin D3 formed in skin from a single exposure to UV sunlight

5 % skina exposed (μg) 10 % skina exposed (μg) 20 % skina exposed (μg)
7-DHCb at 0·5 μg/cm2 458  917  1834 
Vitamin D3 produced at 10 % conversion 46  92  183 
Vitamin D3 produced at 20 % conversion 92  183  367 

The yield of vitamin D3 in skin, in response to exposure to UV light from the sun, depends not only on the number of minutes of a single period of exposure, but also on many other variables, including the seasonal intensity of solar UVB radiation, absorption of UVB radiation by skin pigmentation, the age of the irradiated individual and the proportion of pre-vitamin D3 produced that is then converted by prolonged irradiation, to other non-biologically active products. Experiments with human skin, irradiated in vitro, have found up to 35 % of total 7-DHC that can be converted to pre-vitamin D3 in a single exposure session(16).

a

Based on the calculated total skin area of an adult male of 18 229 cm2(15).

b

Lowest concentration of 7-DHC in skin, which ranges from 0·5–1·3 μg/cm2(12).