Figure 2.
Common packaging of deregulated long non-coding RNAs (lncRNAs) and pseudogenes into SEVs and LEVs from FTD and ALS patients. (A) For FTD, of the 9 lncRNAs in SEVs and 11 in LEVs, 6 were in common (all upregulated, green). (B) For ALS, of the 12 lncRNA in SEVs and 19 in LEVs, 4 were in common (all upregulated, green). Differential lncRNA expression analysis was carried out using DESeq2 (log2FC> 1, p < 0.05).