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. 2022 Feb 16;13:821689. doi: 10.3389/fendo.2022.821689

Table 3.

The association between hyperuricemia and MAFLD by the Cox regression in the longitudinal cohort study.

Baseline hyperuricemia to subsequent MAFLD Baseline MAFLD to subsequent hyperuricemia
HR(95%CI) P-value HR(95%CI) P-value
Crude 2.670 (2.307,3.090) <0.001 Crude 1.765 (1.594,1.955) <0.001
Model 1 2.192 (1.887,2.546) <0.001 Model 1 1.395 (1.257,1.549) <0.001
Model 2 1.766 (1.512,2.061) <0.001 Model 2 1.255 (1.116,1.412) <0.001
Model 3 1.765 (1.512,2.060) <0.001 Model 3 1.245 (1.106,1.400) <0.001

MAFLD, metabolic dysfunction-associated fatty liver disease.

Model 1: adjusted for age and sex.

Model 2: adjusted for age, sex, low-density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), alanine aminotransferase (ALT), blood urea nitrogen (BUN), systolic blood pressure (SBP), triglycerides (TG).

Model 3: adjusted for age, sex, low-density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG), alanine aminotransferase (ALT), blood urea nitrogen (BUN), systolic blood pressure (SBP), triglycerides (TG), insulin resistance.