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. 2022 Feb 25;77:103890. doi: 10.1016/j.ebiom.2022.103890

Table 1.

Primary diagnosis of neonatal cholestasis.

Primary diagnosis for neonatal cholestasis Dataset
Complete-case n = 2661 (%) Whole-case n = 4028 (%)
Prematurity and birth-related issues 654 (24.6%) 1426 (35.4%)
Congenital heart anomaly and other problems 663 (24.9%) 751 (18.6%)
Liver origin diseases including biliary atresia and hepatitis 416 (15.6%) 461 (11.4%)
Gastrointestinal anomaly and other problems 345 (13%) 369 (9.2%)
Neonatal jaundice in healthy newborns 58 (2.2%) 299 (7.4%)
Respiratory anomaly and related issues 178 (6.7%) 222 (5.5%)
Genetic/chromosomal disorders 141 (5.3%) 174 (4.3%)
Renal anomalies and urinary tract issues 55 (2.1%) 81 (2.0%)
Malignancy and tumour 57 (2.1%) 59 (1.5%)
Brain anomalies and other neurologic issues 32 (1.2%) 48 (1.2%)
Infection 15 (0.6%) 43 (1.1%)
Haematologic disorders 16 (0.6%) 38 (0.9%)
Hypopituitarism/hypothyroidism 9 (0.3%) 27 (0.7%)
Others 22 (0.8%) 30 (0.7%)