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. 2022 Feb 16;12:806386. doi: 10.3389/fgene.2021.806386

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Copyright © 2022 Loeffler, Gaisa, Muti, van Treeck, Echle, Ghaffari Laleh, Trautwein, Heij, Grabsch, Ortiz Bruechle and Kather.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap comparing the area under the receiver operating curve (AUROC) between the different tumor types. On the y-axis all tumor types are listed and sorted by tumor with most significant results from top to bottom. Number of patients indicated in brackets behind. Pathways are ordered on the x-axis from most (left) to least (right) significant results. AUROC values for (A) the twelve pathway analysis and (B) for the 69 gene analysis. Coloured values stand for significant detected (p > 0.05) pathways and grey for not significantly (p > 0.05). TCGA tumor type abbreviations are used (https://gdc.cancer.gov/resources-tcga-users/tcga-code-tables/tcga-study-abbreviations).