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In vitro culture influences metaboloepigenetic genes expression
(A–D) Embryo General analysis of in vitro bovine and mouse mature oocyte (MII) and embryos (2, 4, 8, 16C, MO and BL) gene expression of metabolism and epigenetic genes. PCA comparing bovine (A) and mouse (B) in vivo and in vitro samples. Metaboloepigenetic genes up (red) and down (green) regulated (adjusted p value < 0.05) comparing in vitro vs in vivo blastocysts from bovine (C) and mouse (D).
