Table 2.
Univariate analysis of the factors associated with medication non-adherence
| Adherent | Non-adherent | p | |
|---|---|---|---|
| Age* | 48±13 | 41±12 | 0.039 |
| Gender (%) | 1.00 | ||
| Female | 52.0 | 51.7 | |
| Male | 48.0 | 48.3 | |
| Travel distance to outpatient clinic (km)** |
49 | 10 | |
| Travel time to outpatient clinic (km)** | |||
| Duration of disease (years)** | 4.5 | 6 | 0.025 |
| Smoking status (%) | 0.412 | ||
| Non-smoker | 42.7 | 31. 0 | |
| Former smoker | 26.7 | 31.0 | |
| Current smoker | 30.7 | 37.9 | |
| Outpatient visit last year (%) | |||
| Changed residency | 94.6 | 89.7 | 0.334 |
| Transport to hospital (%) | 1.00 | ||
| Own car | 50.7 | 49.1 | |
| Public transport | 32.9 | 33.3 | |
| Both | 16.4 | 17.5 | |
| Medication (%) | |||
| ASA | 92.0 | 93.1 | 1.00 |
| Budesonide | 47.3 | 45.6 | 0.86 |
| Azathioprine | 68.9 | 54.4 | 0.128 |
| Anti-TNF (%) | |||
| Adalimumab | 18.7 | 13.8 | 0.607 |
| Infliximab | 9.3 | 16.1 | 0.371 |
| Education (%) | 0.023 | ||
| Low¥ | 56.0 | 35.7 | |
| High§ | 44.0 | 64.3 | |
| Household Income (%) | 0.972 | ||
| Low | 40.5 | 38.6 | |
| Moderate | 45.9 | 47.4 | |
| High | 13.5 | 14.0 | |
| Crohn’s disease behavior (%) | 0.609 | ||
| Complicated | 17.3 | 22.4 | |
| Not complicated | 82.7 | 77.6 | |
| Disease activity (%) | 0.999 | ||
| Active | 34.7 | 36.2 | |
| Remission | 65.3 | 63.8 | |
*: Mean±SD; **: Median; km: Kilometer; ¥: Education levels lower than high school degree; §: University and college degree; SD: Standard deviation; ASA: American Society of Anesthesiologist; SD: Standard deviation.