Skip to main content
. 2022 Jan 29;298(3):101614. doi: 10.1016/j.jbc.2022.101614

Figure 4.

Figure 4

mtm-10 mutation affects the function of AWC neurons in a cell-autonomous manner.A, representative photomicrographs of mtm-10 animals expressing mtm-10 and GFP under the control of the odr-1 promoter after 24 h of Pseudomonas aeruginosa infection. The scale bars represent 5 μm. B, quantification of the dendrite degeneration phenotype in control CX5974 (parent strain), mtm-10(ac270), and mtm-10(ac270);Podr-1::mtm-10::SL2::GFP animals. The black symbols represent individual data points. (N = 6, number of animals = 50). Control versus mtm-10(ac270)(p < 0.0001) and mtm-10(ac270) versus mtm-10(ac270);Podr-1::mtm-10::SL2::GFP(p < 0.0001) via one-way ANOVA test. C, quantification of chemotaxis index (CI) in control CX5974 (parent strain), mtm-10(ac270), mtm-10(ok2711), mtm-10(ac270);P mtm-10::mtm-10, and mtm-10(ac270);Podr-1::mtm-10::SL2::GFP animals in response to benzaldehyde. Control versus mtm-10(ac270), (p < 0.01) and Control versus mtm-10(ok2711), (p < 0.0001), via one-way ANOVA test. The black symbols represent individual data points (N = 6). ∗∗∗∗p < 0.0001. RFP, red fluorescent protein.