Table 4.
Summary of Ongoing Clinical Trials.
Trial | Author | n | Population | Intervention (mg) | Duration | Measured Endpoints | Result | Ref |
---|---|---|---|---|---|---|---|---|
ALL-HEART | Mackenzie et al. | 5,215 | Ischemic Heart Disease | Allopurinol up to 600 mg daily vs. No treatment | 4 years | Composite of non-fatal myocardial infarction, non-fatal stroke or cardiovascular death. | Patient recruitment began in February 2014 with ongoing data collection and follow-up | [103] |
LEAF-CHF | Yokota et al. | 200 | Chronic HF with Hyperuricemia | Febuxostat 60 mg vs. Control | 24 weeks | Change in plasma BNP levels. | Results Pending with ongoing data collection and follow-up | [123] |