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Distribution of participant numbers, FEUA and RAFs of URAT1 variants along SUA levels
As SUA levels decreased, FEUA and RAFs of non-functional URAT1 variants (R90H and W258X) increased in (A) males, (B) females and (C) all 4993 participants. This trend was more marked in the male population than in the female population. There were no female participants with SUA >9 mg/dl. FEUA: fractional excretion of uric acid; RAF: risk allele frequency; SUA: serum uric acid.
