Detection of potentially pathogenic bacteria (PPB) in the upper respiratory tract of young children with respiratory syncytial virus (RSV) infection and healthy age controls. A, Frequency of nasopharyngeal (NP) bacterial detection in study patients. The horizontal axis represents the study groups and the vertical axis represents the percentage of NP bacterial detection (Streptococcus pneumoniae, Staphylococcus aureus, Moraxella catarrhalis, Haemophilus influenzae): negative detection for any of the 4 bacteria (gray), detection of 1 of these 4 PPB (red), and detection of >1 PPB (green). B, Frequency of NP detection of specific bacteria. Pie charts for healthy controls and children with RSV infection (all, inpatients, and outpatients) showing the percentage detection of none of the 4 bacteria by PCR (gray), S. pneumoniae only (dark blue), S. aureus only (light blue), M. catarrhalis only (dark pink), H. influenzae only (light pink), and >1 PPB (green). C, Radar plot depicting the frequency of any detection of S. pneumoniae, S. aureus, M. catarrhalis, and H. influenzae in children with RSV infection (orange) compared to healthy controls (HC; light yellow). P values indicate the comparisons between RSV and HC for any detection (alone and in combination with other bacteria) of each of the 4 bacteria.