Table 2.
Diagnostic accuracy of FDG grades at key anatomic sites for a diagnosis of PMR
| Anatomic site | AUC in ROC analysis | Visual FDG grade | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|---|
| Ischial tuberosities | 0.865 (0.749–0.981) | ≥1 | 97.4 (86.5, 99.9) | 52.6 (28.9, 75.6) |
| ≥2b | 89.7 (75.8, 97.1) | 78.9 (54.4, 93.9) | ||
| ≥3 | 71.8 (55.1, 85.0) | 84.2 (60.4, 96.6) | ||
| Hips | 0.836 (0.715–0.957) | ≥1 | 100 (91.0, 100.0) | 42.1 (20.3, 66.5) |
| ≥2b | 71.8 (55.1, 85.0) | 84.2 (60.4, 96.6) | ||
| ≥3 | 43.6 (27.8, 60.4) | 89.5 (66.9, 98.7) | ||
| Lumbar interspinous bursa | 0.836 (0.713–0.959) | ≥1 | 92.3 (79.1, 98.4) | 57.9 (33.5, 79.7) |
| ≥2 | 89.7 (75.8, 97.1) | 63.2 (38.4, 83.7) | ||
| ≥3b | 87.2 (72.6, 95.7) | 78.9 (54.4, 93.9) | ||
| Sternoclavicular joints | 0.800 (0.683–0.918) | ≥1b | 71.8 (55.1, 85.0) | 84.2 (60.4, 96.6) |
| ≥2 | 51.3 (34.8, 67.6) | 94.7 (74.0, 99.9) | ||
| ≥3 | 46.2 (30.1, 62.8) | 94.7 (74.0, 99.9) | ||
| Symphysis pubis entheses | 0.785 (0.659–0.910) | ≥1b | 69.2 (52.4, 83.0) | 89.5 (66.9, 98.7) |
| ≥2 | 48.7 (32.4, 65.2) | 89.5 (66.9, 98.7) | ||
| ≥3 | 28.2 (15.0, 44.9) | 94.7 (74.0, 99.9) | ||
| Greater trochanters | 0.781 (0.650–0.912) | ≥1 | 100 (91.0, 100) | 10.5 (1.3, 33.1) |
| ≥2b | 74.4 (57.9, 87.0) | 78.9 (54.4, 93.9) | ||
| ≥3 | 38.5 (23.4, 55.4) | 85 (62.1, 96.8) | ||
| Lumbar facet joints | 0.775 (0.642–0.907) | ≥1b | 69.2 (52.4, 83.0) | 89.5 (66.9, 98.7) |
| ≥2 | 48.7 (32.4, 65.2) | 89.5 (66.9, 98.7) | ||
| ≥3 | 33.3 (19.1, 50.2) | 89.5 (66.9, 98.7) | ||
| Cervical interspinous bursa | 0.769 (0.640–0.898) | ≥1b | 74.4 (57.9, 87.0) | 73.7 (48.8, 90.9) |
| ≥2 | 61.5 (44.6, 76.6) | 84.2 (60.4, 96.6) | ||
| ≥3 | 48.7 (32.4, 65.2) | 89.5 (66.9, 98.7) | ||
| Kneesa | 0.746 (0.586–0.907) | ≥1 | 89.3 (71.8, 97.7) | 33.3 (11.8, 61.6) |
| ≥2b | 64.3 (44.1, 81.4) | 86.7 (59.5, 98.3) | ||
| ≥3 | 32.1 (15.9, 52.4) | 86.7 (59.5, 98.3) | ||
| Shoulders | 0.719 (0.577–0.862) | ≥1 | 97.4 (86.5, 99.9) | 10.5 (1.3, 33.1) |
| ≥2b | 71.8 (55.1–85.0) | 68.4 (60.4, 87.4) | ||
| ≥3 | 43.6 (27.8, 60.4) | 84.2 (28.9, 96.6) | ||
| Iliopectineal bursae | 0.718 (0.590–0.846) | ≥1b | 43.6 (27.8, 60.4) | 100 (82.4, 100.0) |
| ≥2 | 28.2 (15.0, 44.9) | 100 (82.4, 100.0) | ||
| ≥3 | 12.8 (4.3, 27.4) | 100 (82.4, 100.0) |
Data are shown for anatomic sites with an area under the curve (AUC) ≥ 0.700 in the receiver operating characteristic (ROC) analysis. Data were obtained from 39 PMR patients and 19 non-PMR patients unless stated otherwise. For bilateral sites with discordant results, the lowest visual score was used. For the interspinous bursae and facet joints, the highest score was used. aData on knees were obtained from 28 PMR patients and 15 non-PMR patients. bOptimal cut-off point according to Youden Index.