Figure 5.

DNM2 protein expression in healthy human muscle and CNM muscle

(A) Representative DNM2 western blot of total protein extracted from human muscle biopsies. GAPDH and total protein loading were used as loading control. (B) Histograms showing quantification of DNM2 protein signal by densitometry using total protein loading (stain free) as loading control (<20 years n = 6; >20 years n = 6). (C) Individual plot of densitometry of bands corresponding to DNM2 normalized to total protein stain free as a function of age. Control patients are represented by black plots (n = 12) and CNM patients by red plots (n = 5). Individual plot represents mean ± SEM of one to four technical duplicates. Statistical analysis was performed using Spearman correlation (∗p < 0.05).