. 2022 Mar 2;189(3):128. doi: 10.1007/s00604-022-05242-4

Table 1.

Concentrations of general biomarkers of SARS-CoV-2 in patients with varying degrees of infection

Types of biomarkers	Asymptomatic infection	Common (mild/moderate) infection	Severe infection
Viral loads	102.0 ~ 315.0 copies mL⁻¹ (N gene) [7]	10^4.0 ~ 10^7.0 copies mL⁻¹ [8]	10^6.0 ~ 10^8.0 copies mL⁻¹ [9]
Antibodies	IgG: 44.4 ~ 58.8 U mL⁻¹ IgM < 1.0 COI [7]	IgG: 285.8 U mL⁻¹ (peak) IgM: ~ 4.7 COI [7]	IgA: 2.8 ~ 3.2 g L⁻¹ IgG: 7.1 ~ 8.2 g L⁻¹ [10]
Antigens	-	10^3.9 ~ 10^6.0 fg mL⁻¹ [11]	10^6.1 ~ 10^7.2 fg mL⁻¹ [11]

Types of biomarkers

Asymptomatic infection

Common (mild/moderate) infection

Severe infection

Viral loads

102.0 ~ 315.0 copies mL⁻¹ (N gene) [7]

10^4.0 ~ 10^7.0 copies mL⁻¹ [8]

10^6.0 ~ 10^8.0 copies mL⁻¹ [9]

Antibodies

IgG: 44.4 ~ 58.8 U mL⁻¹

IgM < 1.0 COI [7]

IgG: 285.8 U mL⁻¹ (peak)

IgM: ~ 4.7 COI [7]

IgA: 2.8 ~ 3.2 g L⁻¹

IgG: 7.1 ~ 8.2 g L⁻¹ [10]

Antigens

10^3.9 ~ 10^6.0 fg mL⁻¹ [11]

10^6.1 ~ 10^7.2 fg mL⁻¹ [11]