9.

Receiver operating characteristic plots obtained using FISH as the reference standard (panel A) and PCR‐based LOH as the reference standard (panel B) for tests with four or more studies and variation in both sensitivity and specificity. Summary estimates of sensitivity and specificity with 95% credible regions are included along with a hierarchical summary receiver operating characteristic (HSROC) line.

CGH: comparative genomic hybridisation; FISH: fluorescence in situ hybridisation; LOH: loss of heterozygosity; PCR: polymerase chain reaction; SNP: single nucleotide polymorphism.