Parameter description	Probability distribution
Prevalence	Beta (mean = 0.31, SD = 0.13)
Sensitivity of MLPA	Beta (α = 12, β = 2)
Specificity of MLPA	Beta (α = 15, β = 8)
Cost of MLPA	Triangular (minimum 55.35, likeliest 73.08, maximum 93.35)
Sensitivity of real‐time PCR	Beta (α = 15, β = 4)
Specificity of real‐time PCR	Beta (α = 24, β = 1)
Cost of real‐time PCR	Triangular (minimum 106.66, likeliest 142.21, maximum 177.76)
Sensitivity of PCR‐based LOH	Beta (α = 196, β = 48)
Specificity of PCR‐based LOH	Beta (α = 633, β = 42)
Cost of PCR‐based LOH	Triangular (minimum 106.66, likeliest 142.21, maximum 177.76)
Sensitivity of CISH	Beta (α = 20, β = 1)
Specificity of CISH	Beta (α = 18, β = 3)
Cost of CISH	Triangular (minimum 139.46, likeliest 185.95, maximum 232.44)
Sensitivity of aCGH	Beta (α = 19, β = 1)
Specificity of aCGH	Beta (α = 19, β = 4)
Cost of aCGH	Triangular (minimum 175.10, likeliest 233.47, maximum 291.84)
Sensitivity of SNP array	Beta (α = 35, β = 13)
Specificity of SNP array	Beta (α = 64, β = 3)
Cost of SNP array	Triangular (minimum 192.60, likeliest 256.80, maximum 321.00)
Sensitivity of NGS	Beta (α = 73, β = 7)
Specificity of NGS	Beta (α = 166, β = 1)
Cost of NGS	Triangular (minimum 428.15, likeliest 570.87, maximum 713.59)