Table 5.

Summary of mouse models used in single cell sequencing studies of AD

Reference (PMID)	Mouse Model	Brain Region	Age (Month)
32341542	5XFAD	Prefrontal cortex	7, 10
32320664	APP/PS1 IL33 mice, APP/PS1 transgenic mice	Cerebral cortex	10–12
31932797	Trem2_KO mice, Trem2_KO_5XFAD, WT_5XFAD mice	Cortex, Hippocampus	7, 15
31928331	APP23 transgenic mice (B6. Cg-Tg (Thy1-APP)3Somm/J)	Hippocampus	6, 24
29020624	CK, CK-p25	Hippocampus	0wk,1wk, 2wk and 6wk after p25 induction into 3 m-old mouse
28602351	5XFAD	Cortex, Cerebellum	6
32503894	3XTg-AD mice	Subventricular zone and hippocampus	8
32503894	anti-Nk1.1 treated 3XTg-AD	Subventricular zone and hippocampus	7
32579671	5XFAD-CV, 5XFAD-R47H	Cortex and hippocampus	5.5
31902528	Trem2 +/+ mice, Trem2 +/− mice, Trem2 −/− mice	Hippocampus	12–14