Table 1.
Demographics and clinical characteristics of study population.
| Primary TN patients | Healthy controls | ||
|---|---|---|---|
| Sex, n (%) | |||
| Female | 23 (30.3) | 23 (30.3) | N/A |
| Male | 17 (22.4) | 17 (22.4) | N/A |
| Age (years) | 55.76 ± 8.23 | 55.80 ± 8.09 | 0.985 |
| Education (years) | 12.58 ± 3.64 | 13.25 ± 4.17 | 0.837 |
| Disease characteristics | |||
| Pain laterality (left/right) | 17/23 | N/A | N/A |
| Pain duration (years) | 7.08 ± 5.29 | N/A | N/A |
| Attack frequency (times per day) | 5.93 ± 5.78 | N/A | N/A |
| Duration of attack (min) | 1.35 ± 0.74 | N/A | N/A |
| VAS Pain Rating | 5.83 ± 1.72 | N/A | N/A |
| SF-McGill Pain Questionnaire | |||
| SF-MPQ-Total | 13.32 ± 6.82 | N/A | N/A |
| SF-MPQ-Sensory | 8.13 ± 4.15 | N/A | N/A |
| SF-MPQ-Affective | 5.18 ± 2.73 | N/A | N/A |
| Emotional assessment | |||
| HAMA | 4.10 ± 3.37 | N/A | N/A |
| HAMD | 4.25 ± 4.38 | N/A | N/A |
| Brain VBM | |||
| TIV | 1.409 ± 0.116 | 1.445 ± 0.104 | 0.086 |
| GMV | 0.664 ± 0.050 | 0.679 ± 0.044 | 0.065 |
| WMV | 0.516 ± 0.055 | 0.530 ± 0.056 | 0.242 |
| CSF | 0.229 ± 0.034 | 0.235 ± 0.028 | 0.273 |
Demographics presented as () unless otherwise stated. Independent two-samples t test was conducted to compare clinical traits between primary TN patients and healthy controls.
VAS: visual analogue scale; SF-MPQ: short-form McGill pain questionnaire; HAMA: Hamilton anxiety rating scale; HAMD: Hamilton depression rating scale; TIV: total intracranial volume; GMV: gray matter volume; WMV: white matter volume; CSF: cerebral spinal fluid; N/A: not applicable.