Table. Characteristics of Patients.
| Characteristic | Patients, No. (%) (N = 179) |
|---|---|
| Sex | |
| Male | 148 (82.7) |
| Female | 31 (17.3) |
| Age, median (range), y | 46 (22-71) |
| ECOG score | |
| 0 | 63 (35.2) |
| 1 | 116 (64.8) |
| Lines of prior therapy | |
| 1 line | 89 (49.7) |
| ≥2 lines | 90 (50.3) |
| PD-L1 statusa | |
| Negative | 126 (70.4) |
| Positive | 45 (25.1) |
| NA | 8 (4.5) |
| TMB (mutations per megabase)b | |
| <0.95 | 82 (45.8) |
| ≥0.95 | 82 (45.8) |
| NA | 15 (8.4) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; NA, not applicable; PD-L1, programmed death-ligand 1; TMB, tumor mutation burden.
a
Positive is defined as 1% or more of tumor cells expressing PD-L1 by SP142 immunohistochemistry staining.
b
Cutoff value is defined as the median value of TMB.