Table 1.

GRADE^a quality of evidence summary for I-CBT^b and mindfulness RCTs^c and quasi-experimental studies with anxiety score outcomes.

Interventions	Number of participants included in the analysis (N)	Quality of evidence (GRADE)	Intervention versus comparator mean difference (95% CI)
I-CBT interventions	228 from 2 RCTs and 1 quasi-experimental study	Very low because of small sample sizes, moderate risk of bias, differences in the population inclusion criteria, and intervention components	−0.49 (95% CI −0.75 to −0.22) improved anxiety scores in the intervention group
Facilitated interventions	818 from 3 RCTs and 2 quasi-experimental studies	Very low because of small sample sizes, moderate risk of bias, differences in the intervention types, population inclusion criteria, and intervention components	−0.48 (95% CI −0.75 to −0.22) improved anxiety scores in the intervention group

^aGRADE: Grading of Recommendations Assessment, Development and Evaluation.

^bI-CBT: internet-based cognitive behavioral therapy.

^cRCT: randomized controlled trial.