TABLE 5.

Positive and negative predictive value of pp65 antigenemia for CMV disease in different patient settings

Setting	Reference/antigenemia level	No. of patients	Prevalence of CMV disease (%)	Positive predictive value (%)	Negative predictive value (%)
HIV-infected patients	Bek et al. (9)	144	30
	Any positive test			47	95
	More than 5 positive cells/slidea			63	84
	Reynes et al. (140)	138	27
	Any positive test			45	94
	More than 10 positive cells/slide			49	86
	More than 50 positive cells/slide			78	80
	More than 100 positive cells/slide			93	80
	More than 500 positive cells/slide			100	77
	Francisci et al. (58)	49	27
	Any positive test			46	92
	More than 20 positive cells/slide			91	92
	Podzamczer et al. (130)	241	12
	Any positive test			26	97
	More than 10 positive cells per 100,000 cells			65	95
Allogeneic marrow transplant recipients	Boeckh et al. (12, 17)	33	27
	Any positive test			53	91
	More than 1 positive cell/slide			75	72
Kidney transplant recipients	van den Berg et al. (174)	130	17
	Any positive test			41	100
	More than 1 positive cell per 50,000 cells			53	100
	More than 10 positive cells per 50,000 cells			69	96
	More than 100 positive cells per 50,000 cells			75	88

^aNumbers of cells used to prepare slides are listed in Table 4.