Table 1.
Demographics of all samples (N = 584).
| Donor and donor cornea characteristics | |
| Donor age, median (IQR), range, y | 66.0 (58, 72), 18–96 |
| Donor sex, male, n (%) | 373 (63.9) |
| Imported graft, n (%) | 427 (73.1) |
| History of diabetes mellitus, n (%) | 140 (24.0) |
| Cigarettes smoking, n (%) | 323 (55.3) |
| Alcohol consumption, n (%) | 206 (35.3) |
| Drug abuse, n (%) | 73 (12.5) |
| History of LASIK, n (%) | 34 (5.8) |
| Donor lens status, n (%) | |
| Phakic | 487 (84.0) |
| IOL | 97(16.6) |
| Cause of death, n (%) | |
| Cardiac disease | 148 (25.3) |
| Cancer | 147 (25.2) |
| Cerebrovascular accident | 86 (14.8) |
| Respiratory disease | 99 (17.0) |
| Others | 104 (17.7) |
| Refrigerated/on ice, n (%) | 343 (58.7) |
| Time from death to the preservation, median (IQR), range, h | 8.0 (5.9, 11.9), 1.8–26.9 |
| Time from death to operation, median (IQR), range, d | 6.9 (6.0, 7.7), 2.0–9.6 |
| Graft ECD, median (IQR), range, cells/mm2 | 2,637 (2,415, 2,921), 2,010–3,812 |
| Endothelial folds, n (%)* | |
| None | 157 (26.9) |
| Mild to moderate | 427 (73.1) |
| Recipient and surgical characteristics | |
| Recipient age at DSAEK, median (IQR), range, y | 73.5 (67, 79), 15–99 |
| Recipient sex, male, n (%) | 208 (35.6) |
| Etiology, n (%) | |
| FECD | 59 (10.1) |
| LIBK | 192 (32.9) |
| PBK | 137 (23.5) |
| Regraft† | 96 (16.4) |
| Others | 100 (17.1) |
| Recipient lens status at DSAEK, n (%) | |
| Phakic | 244 (41.8) |
| IOL/Aphakic | 340 (58.2) |
| Simultaneous cataract surgery, n (%) | 189 (32.4) |
| Re-bubbling, n (%) | 79 (13.5) |
| Central graft thickness, median (IQR), range, μm‡ | 143 (123, 161), 53–270 |
| Graft diameter, n (%), mm | |
| 6.75–7.75 | 144 (24.7) |
| 8.0–8.75 | 440 (75.3) |
DSAEK, Descemet's stripping automated endothelial keratoplasty; ECD, endothelial cell density; FECD, Fuchs' endothelial corneal dystrophy; IOL, intraocular lens; IQR, interquartile range; LASIK, laser-assisted in situ keratomileusis; LIBK, laser-iridotomy-related bullous keratopathy; PBK, pseudophakic bullous keratopathy.
Grafts without folds were defined as having “no graft folds,” “mild graft folds” were defined by the presence of graft folds limited to <25% of the area of the total cornea, and “moderate graft folds” were defined by the presence of graft folds that occupied more than 25% of the area of the total cornea.
Regraft is included in re-DSAEK (56 eyes), post penetrating keratoplasty (36 eyes), post-deep anterior lamellar keratoplasty (2 eyes) and post-Descemet's membrane endothelial keratoplasty (2 eyes).
Central graft thickness data was obtained in 503 eyes.