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. 2022 Feb 9;62(4):914–926. doi: 10.1021/acs.jcim.1c00840

Table 1. Crystal Structures of Plasmepsin-II (PDB: 2BJU, 2IGY, and 4Z22) and Bovine Chymosin Protease (PDB: 1CMS) Show Different Conformational States of Tyra.

PDB χ1 (radian) DIST2 (nm) State
2BJU –3.12 1.50 F
2IGY –2.6 1.74 F
4Z22 –1.02 2.11 N
1CMS 3.08 1.28 F
a

F and N denote flipped and normal states, respectively.