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. 2022 Mar 2;17:93. doi: 10.1186/s13023-022-02223-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Comparison of salivary changes among NF1 patients and NF1-controls. A Prevalence of decreased salivary flow rate among NF1 patients and NF1- controls (OR = 1.40, 95% CI = 1.05–1.76, P = 0.005). B Whole unstimulated salivary flow rates among NF1 patients and NF1- controls. Y axis represented flow rates (ml/min). X axis represented age of participants. C Salivary amylase activity among NF1 patients and NF1- controls. Y axis represented amylase activity (1/min). X axis represented age of participants. D Salivary pH values among NF1 patients and NF1- controls. Y axis represented pH values. X axis represented age of participants