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. 2022 Mar 2;17:93. doi: 10.1186/s13023-022-02223-x

Table 1.

Presentation of oral complications among NF1 patients and NF1- controls

Index Age subgroups Mean of NF1- controls Mean of NF1 + cases Mean difference (95% CI) = values of NF1 + —that of NF1- P value
Salivary flow rate  < 20 0.340 0.335  − 0.005 (− 0.019–0.0092) 0.45
Salivary flow rate 21–40 0.321 0.293  − 0.029 (− 0.047– − 0.011) 0.005
Salivary flow rate  > 40 0.292 0.173  − 0.12 (− 0.15– − 0.09)  < 0.0001
Amylase activity  < 20 0.387 0.374  − 0.013 (− 0.03–0.0083) 0.15
Amylase activity 21–40 0.377 0.323  − 0.053 (− 0.075– − 0.033) 0.0008
Amylase activity  > 40 0.360 0.292  − 0.068 (− 0.089– − 0.047)  < 0.0001
Salivary pH value  < 20 7.04 7.08 0.032 (− 0.068–0.13) 0.49
Salivary pH value 21–40 7.10 7.80 0.70 (0.46–0.94)  < 0.0001
Salivary pH value  > 40 7.17 8.27 1.10 (0.911.27)  < 0.0001
PI  < 20 0.49 0.66 0.16 (− 0.016–0.35) 0.07
PI 21–40 1.46 3.70 2.25 (0.69–3.80) 0. 009
PI  > 40 4.80 6.53 1.73 (0.16–3.31) 0.03
DMFT score  < 20 1.86 1.25  − 0.61 (− 2.80–1.59) 0.55
DMFT score 21–40 4.62 9.5 4.88 (0.33–9.41) 0.04
DMFT score  > 40 7.71 22.67 14.95 (12.44–17.47)  < 0.0001