Table 1.

Vaccine candidates.

Vaccine	Genetic characteristics	Relevant phenotype	References
Rev1::wbdRΔwbkC	Rev 1 wbkC (formyl-transferase gene) deleted mutant carrying a mini-Tn7 insert with E. coli O157:H7 wbdR (acetyl-transferase)	S-LPS with N-acetyl-perosamine O-PS	[19]
H38ΔwbkF	B. melitensis H38 wbkF (bactoprenol priming for O-PS polymerization gene) deleted mutant	R-LPS with intact core oligosaccharide	This work
Bov::CAΔwadB	B. ovis PA wadB (core sugar glycosyl transferase gene) deleted mutant carrying a mini-Tn7 insert with the carbonic anhydrases (CAI and CAII) genes of B. abortus 2308 W	CO2-independent; R-LPS with a truncated core oligosaccharide	This work. ΔwadB and::CA single mutants in [27] and [30], respectively