| Peripheral neuropathy |
Neuropathic pain (Fabry crises) |
Present or past experience of neuropathic pain |
| Hypohidrosis, heat intolerance |
Hypohidrosis, heat intolerance |
| Hearing loss, vertigo |
Hearing loss, vertigo |
| Nausea, vomiting, diarrhea |
Nausea, vomiting, diarrhea |
| Abdominal pain |
Abdominal pain |
| Postprandial bloating and pain, early satiety |
Postprandial bloating and pain, early satiety |
| Difficulty gaining weight |
Difficulty gaining weight |
| Cerebrovascular involvement |
Cerebral microvascular ischemic involvement |
Significant white matter lesions |
| Transient ischemic attacks |
| Ischemic strokes |
| Neuropsychiatric phenotype |
| Renal |
Microalbuminuria, proteinuria |
Albuminuria overt proteinuria |
| Progressive chronic kidney disease |
| Kidney failure |
| End-stage renal disease necessitating renal replacement treatments |
| Cardiac |
Impaired heart rate variability |
Left ventricular hypertrophy |
| Arrhythmias |
Hypertrophic cardiomyopathy |
| ECG abnormalities (shortened PR interval) |
Cardiac arrhythmias |
| Mild valvular insufficiency |
Valvular disease |
| Aortic dilatation at Valsalva sinuses |
| Dermatological |
Angiokeratomas |
Angiokeratomas |
| Sweating abnormalities (hypohidrosis) |
Linear telangiectasia |
| Lymphedema |
| Hypotrichosis |
| Ocular |
Corneal deposits (cornea verticillata) and lenticular opacities |
Corneal deposits (cornea verticillata) and lenticular opacities |
| Vasculopathy (conjunctiva, retina) |
Vasculopathy (conjunctiva, retina) |
