Fig. 5.

A–C The ROC curves of the selected gene panels and confusion matrices in the training set (A), the internal validation set (B), and the external validation set (C). D The ROC curves of the training set (via LOOCV) and the internal validation set by including CEA and CA199 into the set of selected genes. SP, specificity; SN, sensitivity. E The ROC curves of the selected genes in the classification of CRC stage